In our approach to sample processing management, we aim at analysing and defining the most effective methods for handling all stages of sample processing. Our focus extends to two areas: lean workflow and process automation.
The lean workflow method involves scheduling short runs throughout the day for thin samples and biopsies, while reserving longer processing times for thick and fatty tissues overnight. This strategy notably enhances workload distribution by transforming idle daytime hours into productive ones. Moreover, it enables the preparation of samples for embedding and cutting within the same day, thus reducing the workload for the following morning. Milestone tissue processors facilitate this approach by employing rapid processes, tailored protocols for small samples and using dual cavities to simultaneously run two processes.
Also process automation is a crucial aspect, as it supports a lean organization, enhancing efficiency, reducing manual processing errors, and reallocating operator time to other tasks. Synergy Milestone autoembedding system, allows to skip manual operation and perform the embedding step directly during tissue processing. This reduces both time and costs while enhancing sample safety by minimizing the risk of damage or loss.

As for operator safety, it is imperative for operators to utilize non-hazardous reagents, such as isopropanol instead of xylene, and to minimize direct exposure to them. Milestone processors ensure ventilation both in the workspace and drawer, as well as the utilization of commercial tanks to eliminate the need for risky manual refilling.
The quality of the sample itself is closely tied to the quality of the reagents used in processing. Therefore, it’s important to prevent direct contamination between water-based and alcohol-based reagents. This is achieved through structural elements that separate the two circuits or, as previously mentioned, sensors that monitor their purity. Advanced processors, such as Milestone units, employ safety modes to protect samples during malfunctions or power failures.

Implementing lean workflow and automation, simplifying and securing reagent management and ensuring full traceability are key strategies for achieving a redesigned laboratory workflow tailored to reduce costs, increase efficiency and maintain the highest levels of quality and safety.