One Multifunctional Device for All Major Applications
KOS is a multifunctional, bench top microwave processor. Built to process up to 110 cassettes at a time, KOS is ideal for smaller labs without large volumes or those in need of a processor that can also fulfill other functions within the lab. The multifunctional design of KOS allows it to be used successfully for many applications, including: rapid tissue processing, decalcification, special stains, fixation, gross hardening and antigen retrieval.
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Flexibility of Applications -
Operator Safety -
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Standardized and Documented Protocols -
Ease of Use
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HIGH DEFINITION MONITOR
enables to watch the process inside the chamber through a dedicated camera
TOUCHSCREEN 8″ TERMINAL
with user-friendly icons
STAINLESS STEEL TRAY
for extra bench space
CONNECTION TO FUME EXTRACTION
to improve operator safety
BUILT-IN CHARCOAL FILTER
for additional protection against formalin fumes
IR LASER SENSOR
for temperature control
STIRRING DEVICE
to constantly keep the specimen in contact with fresh reagent
Fast. Unmatched tissue processing time.
For transplant biopsies including fixation.
For 1 mm biopsies.
Add 13 minutes to include fixation.
Add 13 minutes to include fixation.
For 2 mm biopsies.
Add 18 minutes to include fixation.
Add 18 minutes to include fixation.
For 3 mm biopsies.
Add 30 minutes to include fixation.
Add 30 minutes to include fixation.
Rapid tissue processing
Rapid tissue processing is the primary application requested by most KOS users. KOS is a semi-automatic tissue processor and requires minimal interaction from the user: simply following the prompts on the icon-driven touchscreen terminal, the operator will move the tissues from fixation through dehydration, clearing and wax infiltration.
A set of pre-stored programs and three specially developed Histomodules are available to meet the processing needs of any laboratory. Small batches of 1 to 4 cassettes utilize the 4K module; this allows flexibility for urgent processing of transplant or biopsies in as little as thirty minutes. Process up to 45 cassette batches using the 45K module, or increase capacity with the new 110 Cassette configuration.
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Antigen Retrieval
Nowadays, most of the laboratory devices do have protocols with antigen retrieval on board. But for some types of antibodies, it is necessary to perform the antigenic unmasking at very high temperatures.
Through dedicated modules, KOS allows to reach these temperatures in a short time. The protocols can be easily set up by selecting temperature, time and histomodules.
Through dedicated modules, KOS allows to reach these temperatures in a short time. The protocols can be easily set up by selecting temperature, time and histomodules.
Request a Virtual Demo
Request a Virtual Demo
Fixation
Milestone has developed three different fixation modules of up to 110 cassettes.
Users can select the time at temperature protocol to fulfill all requirements of standardization and documentation for CAP/ASCO for HER2/ER.
Through the microwave exposure and optimized protocol at 50°C, KOS allows for faster fixation times, consistent results, complete and standardized fixation even in heterogeneous batches.
Through the microwave exposure and optimized protocol at 50°C, KOS allows for faster fixation times, consistent results, complete and standardized fixation even in heterogeneous batches.
Gross Hardening
Through a specific module, operators can perform gross hardening in the KOS unit. The gross specimen is hardened through microwave heating-induced coagulation of the proteins, while the tissue is immersed in saline solution. Preset protocols at 50° C and 65° C, with formalin and saline solution respectively, guarantee consistent results.
Electron Microscopy
KOS allows to perform rapid processing system for electron microscopy: through a dedicated kit and preset programs for different kind of resins, samples can be processed in 4 hours (polymerization included).
The design of the KOS EM system allows closed vessel processing from fixation through 100% resin, limiting to a minimum the operator’s exposure to toxic reagents. To avoid handling each individual specimen, all specimens are placed in processing cassettes stacked on a spindle that can hold 24 samples (6 cassettes of 4 samples each) or 48 samples (4 cassettes of 8 samples each).
This allows a simultaneous transfer of all the specimens from vial to vial.
The design of the KOS EM system allows closed vessel processing from fixation through 100% resin, limiting to a minimum the operator’s exposure to toxic reagents. To avoid handling each individual specimen, all specimens are placed in processing cassettes stacked on a spindle that can hold 24 samples (6 cassettes of 4 samples each) or 48 samples (4 cassettes of 8 samples each).
This allows a simultaneous transfer of all the specimens from vial to vial.
