SYNERGY
Auto-embedding System:
Processing + Embedding All-in-One
Skip the Manual Embedding Step
Embedding represents one of the most critical bottlenecks in the histology workflow. This time-consuming procedure is carried out manually, and it is therefore operator dependent.
Synergy technology eliminates the need to reopen the cassettes and reorient the tissues. The dedicated rack and consumables, in combination with Milestone tissue processors, allow the automatic embedding of up to 45 cassettes per run, regardless of the size and type of tissue. Synergy completely removes the tedious embedding step by utilizing a single tissue processing and embedding protocol.
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Optimized Laboratory Workflow -
Optimal Flat Positioning of Specimens -
Reduced Turnaround Time -

High Flexibility
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Time and Cost Savings
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Easy and Fast Cassette Preparation
Step 1
Place the specimen in the plastic mold and cover it with the special pad.
Step 2
Clip the standard cassette as a cover of the mold.
Step 3
Place the assembled mold in the Synergy rack slot. Load the rack into your Milestone tissue processor.
From Auto-Embedding to the Cutting Step
Step 4
At the end of the automatic tissue processing and embedding steps, slide out the cassettes from the rack and place them on a cold plate.
Step 5
The easy opening of the mold enables a quick release of the specimen for cutting.
Step 6
With the Synergy method, trimming time is reduced. There is no need to modify your standard cutting procedure at the microtome.
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Patented Technology for Processing + Embedding in One Step
The innovative Synergy technology allows operators to perform simultaneously processing plus embedding. The unique design of the rack enables the movement of the mold+cassette into two positions during the processing step. Through a leverage system, the ring placed at the bottom of the processor retort moves the mold+cassette from an angled for the processing step, to a horizontal for the embedding step.
Angled Position
During fixation and through all other reagent steps, the molds in the rack are held at an angled position.
This allows free circulation of reagents, and the fluids can flow in and out without retention.
This allows free circulation of reagents, and the fluids can flow in and out without retention.
Horizontal Position
At the end of wax impregnation, the rack is automatically lifted by the processor, and the molds are held at a horizontal position to collect the required paraffin and automatically embed the tissue.
High flexibility
Synergy is available in multiple configurations to optimize the process based on specimen type. A suite of molds and pads, available in various sizes and shapes, ensures the best outcome from each individual run.
- The STANDARD KIT (A) is used for embedding larger samples.
- The NEEDLE KIT (B) is used for narrow and long samples.
- The BIOPSY KIT (C) is used for biopsies and fragments.
The use of the pad always depends on the thickness of the specimen.
Related products
The SYNERGY technology for processing plus embedding fits all Milestone’s automatic and semi-automatic tissue processors.
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