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for High Quality Frozen Sections

Process and Stain Permanent-Like Quality Frozen Sections

PRESTO PRO is an innovative bench top processor/stainer designed to deliver high quality results for frozen sections by providing a standardized and automated approach to processing and staining up to 6 frozen slides simultaneously. Its configuration ensures reproducible, consistent, and high quality intraoperative frozen sectioning and accommodates increased workloads.
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to ensure the safety of laboratory personnel


to move a rack of 6 slides


for full documentation


to set and customize process parameters


for the processing and staining phases

High Quality Results

Pathologists rely heavily on the frozen section technique for intra-operative consultation when the surgeon requires a rapid diagnosis or immediate feedback regarding surgical margins. Frozen sections offer a short turnaround time (15-20 minutes) but usually have the disadvantage of lower diagnostic quality than paraffin sections due to cryoembedding artifacts and variability in staining protocols. Milestone offers a new approach to overcome these limitations by combining the artifact-free freezing process of PrestoCHILL with the superior processing and staining capabilities of PRESTO PRO. The advantage of PRESTO PRO is that it provides a standardized and reproducible process that is capable of both efficient processing and staining protocols. This results in improved morphology of the analyzed specimens and maintains a high standard of result quality.

Automatic & Standardized

PRESTO PRO automates processing and staining by using an automated arm to move the rack, capable of holding 6 slides, to the correct vessel on a circular platform.
The PRESTO PRO arm lowers and lifts the rack into and out of the vessels, starting with a heated FineFIX fixation, followed by other customizable staining steps.
Automation of the process ensures standardized, reproducible, and superior quality results, regardless of operator skill.
Heated fixation protocol

Heated fixation protocol

Position the slide rack over the FineFIX processing vessel.
Staining protocols

Staining protocols

The transport arm automatically moves the rack through all customizable staining vessels.
Slides are ready for coverslipping

End of process

The slides are ready for cover slipping and examination.
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High Productivity

To improve workflow and increase productivity in high-volume frozen section laboratories, PRESTO PRO introduces continuous loading.
This uses two racks of 6 slides each, with the second rack loaded into the FineFIX container less than 2 minutes after the first rack is started. While the slides are automatically stained, the operator can simultaneously perform other lab tasks, such as cryoembedding and sectioning new specimens.

Single Loading

High-Quality protocol

High-Quality protocol
2’20” for six slides
120 slides/hour*

Ultra-Quality protocol

Ultra-Quality protocol
4’00” for six slides
80 slides/hour*

Continuous Loading

High-Quality protocol

High-Quality protocol in continuous loading
2’20” for six slides
194 slides/hour*
Enhanced Safety

Enhanced Safety

PRESTO PRO ensures lab personnel safety with an integrated ventilation system and optional filter kit, reducing exposure to chemicals. It uses green reagents, such as isopropanol (instead of xylene) and FineFIX, a patented ethanol-based fixation and processing reagent. Its formulation overcomes limitations of pure ethanol or formalin-based fixatives.
The system supports secure traceability with a barcode reader. Additionally, the USB port allows for software updates and download of event logs and saved runs.

Customizable Protocols

PRESTO PRO is easy to implement in a variety of laboratory environments and offers a wide range of features, including full protocol customization for each tissue, based on the pathologist’s requirements, through an intuitive, user-friendly interface. It also operates as an open system, allowing to use your own staining reagents.
Thanks to its compact size, PRESTO PRO fits into any laboratory setup, ensuring fast processing of even the most urgent samples.
Customizable Protocols

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