The Science of Cryoembedding for High-Quality Frozen Sections


It’s time to revolutionize the rapid freezing process

PrestoCHILL reduces freezing time to 60 seconds: it eliminates freezing artifacts through ultrafast freezing, preventing the formation of ice crystals. Cut fatty tissues like breast or lymph nodes can be freezed without any sort of difficulty and without the distortion of delicate honeycomb structures.

It is possible to obtain perfectly “flat plane” surfaces to reduce trimming time and to cut easily while using the patented “face down” embedding technique.

  • No freezing artifacts
  • 60 seconds freezing time
  • An all-dry system
  • Full downloadable documentation
  • No liquid nitrogen
  • No Co2 – No isopentane
Lung Cancer 40x
Lung Cancer 40x
High Quality JPG
Breast Cancer 40x
Breast Cancer 40x
High Quality JPG

Breast 40x
High Quality JPG

Tyroid 20x
High Quality JPG

Why PrestoCHILL?

    Standardized freezing at -40°C for all types of tissues, even for the most difficult to cut at the cryostat (such as breast, lymph nodes). Rapidly change out molds with a range of different sizes and designs.
  • FAST
    Only 40 minutes from room to the operating temperature of -40°C. At the set temperature, 6 biospecimens can be frozen simultaneously in only 60 seconds. Reduced trimming time at the cryostat state through specimen planarity in the cryo- embedding compound.
  • SAFE
    No liquid nitrogen, no CO2, no isopentane. No operations inside the cryostat chamber during the freezing step. HEPA cap filter.
    The technologically advanced Stirling cooler uses Helium gas as a refrigerant in a sealed stainless steel chamber. No standard compressor is used, therefore no CFCs (Chlorofluorocarbons).
    A USB port enables both software update and event log downloads.
    Its reduced dimensions occupy minimum space in restricted lab environments.

The perfect cryoembedding composition for the PrestoCHILL system

MCC is a proprietary formulation of glycols and resins specifically developed for optimal support during cryotomy of dissected tissues down to -40°C.

Being water soluble, MCC doesn’t leave residue on the slides, eliminating non specific background staining. Additionally, MCC will not dull microtome knives.


Have questions?