{"id":1468,"date":"2023-02-08T15:52:54","date_gmt":"2023-02-08T15:52:54","guid":{"rendered":"https:\/\/www.milestonemedsrl.com\/us\/?page_id=1468"},"modified":"2025-09-16T13:46:24","modified_gmt":"2025-09-16T13:46:24","slug":"tissuesafe-plus","status":"publish","type":"page","link":"https:\/\/www.milestonemedsrl.com\/us\/products\/safe-formalin-handling\/tissuesafe-plus\/","title":{"rendered":"TissueSAFE Plus"},"content":{"rendered":"<div>\n<h3>TissueSAFE plus<\/h3>\n<p><h4><strong>Vacuum Sealing System<\/strong><\/h4>\n<\/p>\n<div>\n<div class=\"uk-margin-top uk-visible@m\">\n<a class=\"uk-button uk-button-primary\" href=\"#modal-media-vimeo\" uk-toggle>Play Video <span uk-icon=\"icon: play-circle\"><\/span><\/a><br \/>\n<a class=\"uk-button uk-button-primary uk-margin-small-left\" href=\"#modal-form\" uk-toggle>Questions <span uk-icon=\"icon: question\"><\/span><\/a>\n<\/div>\n<div class=\"uk-margin-top uk-hidden@m\">\n<a class=\"uk-button uk-button-primary uk-margin-small-top\" href=\"#modal-media-vimeo\" uk-toggle>Play Video <span uk-icon=\"icon: play-circle\"><\/span><\/a><br \/>\n<a class=\"uk-button uk-button-primary uk-margin-small-top\" href=\"#modal-form\" uk-toggle>Questions <span uk-icon=\"icon: question\"><\/span><\/a>\n<\/div>\n<div id=\"modal-media-vimeo\" class=\"uk-flex-top\" uk-modal>\n<div class=\"uk-modal-dialog uk-width-auto uk-margin-auto-vertical\">\n        <button class=\"uk-modal-close-outside\" type=\"button\" uk-close><\/button><br \/>\n        <iframe loading=\"lazy\" src=\"https:\/\/player.vimeo.com\/video\/912255685\" width=\"1280\" height=\"720\" uk-video uk-responsive><\/iframe>\n    <\/div>\n<div id=\"modal-form\" class=\"uk-flex-top\" uk-modal>\n<div class=\"uk-modal-dialog uk-modal-body uk-margin-auto-vertical \">\n        <button class=\"uk-modal-close-outside\" type=\"button\" uk-close><\/button><\/p>\n<h3 class=\"uk-heading-bullet\">Have questions?<\/h3>\n\n\t\t\t\t\t\t<script>\n\t\t\t\t\t\t\twindow.hsFormsOnReady = window.hsFormsOnReady || [];\n\t\t\t\t\t\t\twindow.hsFormsOnReady.push(()=>{\n\t\t\t\t\t\t\t\thbspt.forms.create({\n\t\t\t\t\t\t\t\t\tportalId: 9033646,\n\t\t\t\t\t\t\t\t\tformId: \"d966b92c-3341-49c7-b285-c39e778f6e16\",\n\t\t\t\t\t\t\t\t\ttarget: \"#hbspt-form-1778696358000-1770448258\",\n\t\t\t\t\t\t\t\t\tregion: \"na1\",\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t})});\n\t\t\t\t\t\t<\/script>\n\t\t\t\t\t\t<div class=\"hbspt-form\" id=\"hbspt-form-1778696358000-1770448258\"><\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n<p><a href=\"https:\/\/www.milestonesrl.com\/images\/milestone\/products\/digestion\/ultrawave3\/UltraWAVE3Innovative-features.mp4\"><\/a><\/p>\n<\/div>\n<h3>Formalin-Free Biospecimen Collection<\/h3>\n<div>TissueSAFE plus is an innovative and patented vacuum system that allows the <strong>preservation of fresh tissues<\/strong> in their natural state, <strong>without fixative<\/strong>. Right after excision, specimens are placed into dedicated bags and sealed under vacuum, thus eliminating the need for formalin in the OR.<br \/>\nTissueSAFE plus also allows <strong>traceability and documentation of the biospecimen transfer<\/strong> from the surgical theater to the histopathology lab.<\/div>\n<ul>\n<li>\n<p>        <img decoding=\"async\" src=\"\/us\/wp-content\/uploads\/2023\/11\/icon-user-safety-1.png\" alt=\"Operator Safety\"><\/p>\n<p><a href=\"#safety\">Operator Safety<\/a><\/p>\n<\/li>\n<li>\n<p>        <img decoding=\"async\" src=\"\/us\/wp-content\/uploads\/2023\/06\/icon-formalin-transfer.png\" alt=\"Documented Formalin-Free Transfer\"><\/p>\n<p><a href=\"#transfer-control\">Documented Formalin-Free Transfer<\/a><\/p>\n<\/li>\n<li>\n<p>        <img decoding=\"async\" src=\"\/us\/wp-content\/uploads\/2023\/06\/icon-control-fixation.png\" alt=\"Control on Tissue Fixation\"><\/p>\n<p><a href=\"#transfer-control\">Control of Tissue Fixation<\/a><\/p>\n<\/li>\n<li>\n<p>        <img decoding=\"async\" src=\"\/us\/wp-content\/uploads\/2023\/06\/icon-preservation.png\" alt=\"Optimal Morphological Preservation\"><\/p>\n<p><a href=\"#preservation\">Optimal Morphological Preservation <\/a><\/p>\n<\/li>\n<li>\n<p>        <img decoding=\"async\" src=\"\/us\/wp-content\/uploads\/2023\/06\/icon-archiving.png\" alt=\"Improved Archiving\"><\/p>\n<p><a href=\"#archiving\">Improved Archiving<\/a><\/p>\n<\/li>\n<\/ul>\n<ul>\n<li>\n<div><a class=\"uk-button uk-button-default\" href=\"#modal-quote\" uk-toggle>Request a quote <span uk-icon=\"icon: file-edit\"><\/span><\/a><\/p>\n<div id=\"modal-quote\" class=\"uk-flex-top\" uk-modal>\n<div class=\"uk-modal-dialog uk-modal-body uk-margin-auto-vertical\">\n        \t<button class=\"uk-modal-close-outside\" type=\"button\" uk-close><\/button><\/p>\n<h3 class=\"uk-heading-bullet\">Request a quote<\/h3>\n\n\t\t\t\t\t\t<script>\n\t\t\t\t\t\t\twindow.hsFormsOnReady = window.hsFormsOnReady || [];\n\t\t\t\t\t\t\twindow.hsFormsOnReady.push(()=>{\n\t\t\t\t\t\t\t\thbspt.forms.create({\n\t\t\t\t\t\t\t\t\tportalId: 9033646,\n\t\t\t\t\t\t\t\t\tformId: \"f82ecb38-b753-4c96-b0da-a94dbda82e2d\",\n\t\t\t\t\t\t\t\t\ttarget: \"#hbspt-form-1778696358000-8903568797\",\n\t\t\t\t\t\t\t\t\tregion: \"na1\",\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t})});\n\t\t\t\t\t\t<\/script>\n\t\t\t\t\t\t<div class=\"hbspt-form\" id=\"hbspt-form-1778696358000-8903568797\"><\/div><\/div>\n<\/div>\n<\/div>\n<\/li>\n<li>\n<div>\n<p><a class=\"uk-button uk-button-default\" href=\"\/us\/wp-content\/uploads\/sites\/3\/2025\/09\/TissueSAFE-plus-CAT316EN-004.pdf\" data-wplink-edit=\"true\">View Brochure <span uk-icon=\"icon: file-text\"><\/span><\/a><\/p>\n<\/div>\n<\/li>\n<\/ul>\n<p><img decoding=\"async\" src=\"\/us\/wp-content\/uploads\/2023\/06\/front-unit.jpg\" alt=\"SealSAFE\"><\/p>\n<ul>\n<li>\n<h3>BARCODE READER<\/h3>\n<div>for specimen data or Patient case ID entry<\/div>\n<\/li>\n<li>\n<h3>CONTROL PANEL<\/h3>\n<div>to set process parameters<\/div>\n<\/li>\n<li>\n<h3>DATA LOGGER PORT<\/h3>\n<div>to monitor time and temperature for documented transportation<\/div>\n<\/li>\n<li>\n<h3>EXTRA SPACE<\/h3>\n<div>to store the dedicated vacuum bags<\/div>\n<\/li>\n<li>\n<h3>HEPA FILTER <\/h3>\n<div>for pathogenic agents<\/div>\n<\/li>\n<li>\n<h3>ACTIVE CHARCOAL FILTER<\/h3>\n<div>for protection against vapors\/odors<\/div>\n<\/li>\n<\/ul>\n<div>\n<p>        <img decoding=\"async\" src=\"\/us\/wp-content\/uploads\/2023\/05\/zero-formalin.png\" alt=\"Zero Formalin Exposure\"><\/p>\n<h3>Zero Formalin Exposure<\/h3>\n<div>In today&#8217;s laboratories, formaldehyde is still used as the standard fixative for collecting and storing biospecimens, although it is well known for being carcinogenic (cancer causing). <br \/>\nOR personnel risk high levels of exposure to formaldehyde fumes in their daily tasks, when handling biospecimens that need to be transferred from the surgical theater to the pathology department.<br \/>\nTissueSAFE plus has been designed to completely remove the operator\u2019s exposure and contact with formalin, as it allows users to collect biospecimens under vacuum, <strong>maintaining the tissue in its \u201cas fresh\u201d conditions<\/strong>.\n<\/div>\n<p><a href=\"\/us\/products\/safe-formalin-handling\/zero-formalin-exposure\/\">Discover more <span uk-icon=\"icon: arrow-right\"><\/span><\/a><\/p>\n<\/div>\n<ul>\n<li>\n<h3>Documented Formalin-Free Transfer<\/h3>\n<div>At the end of the vacuum sealing process, the TissueSAFE plus <strong>prints a label with the most relevant information<\/strong> (Case ID, user, date, time, etc.) for complete documentation.<br \/>\nMoreover, a dedicated Data Logger Card can be activated at the start of the shift and then placed into the transfer box to continuously <strong>monitor and document tissue temperature and transfer time<\/strong> from the surgery suite to the histology lab. <br \/>\nAt accessioning, the technician can download all the relevant specimen data from the Data Logger Card, review the cases and print reports.<br \/>\n<img decoding=\"async\" src=\"\/us\/wp-content\/uploads\/2023\/06\/data-logger.jpg\" alt=\"Documented Formalin-Free Transfer\" class=\"uk-margin-top\"><\/div>\n<\/li>\n<li>\n<h3>Controlled Conditions for Tissue Fixation<\/h3>\n<div>Through the dedicated TissueSAFE plus vacuum-sealed bags, tissues are transported fresh to the pathology lab.<br \/>\nBy removing air from the bags, a controlled environment is created, minimizing the risk of external factors that could compromise the fixation process. This enables operators to <strong>perform fixation under controlled conditions<\/strong>, thus optimizing the preservation and quality of the tissue samples. <br \/>\nWith this level of control, pathologists can carry out accurate and consistent tissue fixation, facilitating reliable histological examinations, molecular studies, and subsequent analysis.<br \/>\n<img decoding=\"async\" src=\"\/us\/wp-content\/uploads\/2024\/01\/controlled-conditions.jpg\" alt=\"Controlled Conditions for Tissue Fixation\" class=\"uk-margin-top\"><\/div>\n<\/li>\n<\/ul>\n<div><a class=\"uk-button uk-button-default\" href=\"#modal-demo\" uk-toggle>Request a Virtual Demo <span uk-icon=\"icon: video-camera\"><\/span><\/a><\/p>\n<div id=\"modal-demo\" class=\"uk-flex-top\" uk-modal>\n<div class=\"uk-modal-dialog uk-modal-body uk-margin-auto-vertical\">\n        \t<button class=\"uk-modal-close-outside\" type=\"button\" uk-close><\/button><\/p>\n<h3 class=\"uk-heading-bullet\">Request a Virtual Demo<\/h3>\n\n\t\t\t\t\t\t<script>\n\t\t\t\t\t\t\twindow.hsFormsOnReady = window.hsFormsOnReady || [];\n\t\t\t\t\t\t\twindow.hsFormsOnReady.push(()=>{\n\t\t\t\t\t\t\t\thbspt.forms.create({\n\t\t\t\t\t\t\t\t\tportalId: 9033646,\n\t\t\t\t\t\t\t\t\tformId: \"f30be08d-9da6-4f57-8817-6b0dcaba2a66\",\n\t\t\t\t\t\t\t\t\ttarget: \"#hbspt-form-1778696358000-8939609838\",\n\t\t\t\t\t\t\t\t\tregion: \"na1\",\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t})});\n\t\t\t\t\t\t<\/script>\n\t\t\t\t\t\t<div class=\"hbspt-form\" id=\"hbspt-form-1778696358000-8939609838\"><\/div><\/div>\n<\/div>\n<\/div>\n<div>\n<p>    <img decoding=\"async\" src=\"\/us\/wp-content\/uploads\/2023\/06\/fixation.jpg\" alt=\"Optimal morphological preservation\"><\/p>\n<h3>Optical Morphological Preservation<\/h3>\n<div>The TissueSAFE plus vacuum sealing system is designed to ensure optimal preservation of tissue morphology, safeguarding the integrity and quality of all tissue types for up to 48-72 hours. <br \/>\nResearch and studies in laboratories worldwide have consistently reported superior results in terms of preservation of cellular structures, prevention of shrinkage or expansion, and maintenance of accurate tissue size and shape.\n<\/div>\n<p><a href=\"\/us\/publications\/#sample-handling\">Read the Publication <span uk-icon=\"icon: arrow-right\"><\/span><\/a><\/p>\n<\/div>\n<p><img decoding=\"async\" src=\"\/us\/wp-content\/uploads\/2023\/06\/plastic-bags.jpg\" alt=\"Plastic bags\"><\/p>\n<h3>Improved Archiving<\/h3>\n<div>The use of high quality, durable plastic bags dramatically reduces the space for storage at the accessioning stage as well as for archiving. Compared to the traditional specimen buckets, TissueSAFE plus vacuum bags <strong>take up less than 80% of typical required space<\/strong>. Furthermore, the use of the bags dramatically decreases the volume of waste, thus saving money on waste management. When disposed, the plastic material used for the bags is dioxin-free, reducing the impact on the environment. <br \/>\nTissueSAFE plus special vacuum bags are available in 6 different dimensions, to <strong>fit any kind of specimen<\/strong> and feature 3 pre-set sealing areas to allow for multiple uses per bag.<\/div>\n<p><p>\n        <a href=\"\/us\/products\/consumables\/#transport\">Discover More<\/a>\n    <\/p>\n<\/p>\n<h3><strong>Standard<\/strong> and <strong>Self-standing<\/strong> options<\/h3>\n<ul>\n<li>\n<p>        <img decoding=\"async\" src=\"\/us\/wp-content\/uploads\/2023\/05\/bag-small.png\" alt=\"Small bag\"><\/p>\n<h2>SMALL SIZE<\/h2>\n<\/li>\n<li>\n<p>        <img decoding=\"async\" src=\"\/us\/wp-content\/uploads\/2023\/05\/bag-medium.png\" alt=\"Medium bag\"><\/p>\n<h2>MEDIUM SIZE<\/h2>\n<\/li>\n<li>\n<p>        <img decoding=\"async\" src=\"\/us\/wp-content\/uploads\/2023\/05\/bag-large.png\" alt=\"Large bag\"><\/p>\n<h2>LARGE SIZE<\/h2>\n<\/li>\n<\/ul>\n<p><img decoding=\"async\" src=\"\/us\/wp-content\/uploads\/2023\/06\/MileWatch-logo-white.png\" alt=\"MileWATCH\"><\/p>\n<h2>MileWATCH<\/h2>\n<h2>24\/7 Tracking and Monitoring<\/h2>\n<div>\n<h3>Track, monitor and manage specimens throughout their journey.<br \/> <a class=\"uk-button uk-button-small uk-button-primary uk-margin-top\" href=\"\/us\/products\/tracking-systems\/milewatch\/\">Discover More<\/a><\/h3>\n<\/div>\n<h2>Related products<\/h2>\n<h2>Resources<\/h2>\n<ul>\n<li>\n<p>        <img decoding=\"async\" src=\"\/us\/wp-content\/uploads\/2023\/03\/icon-webinar-green.png\" alt=\"Webinar\"><\/p>\n<h3>Webinars  <span uk-icon=\"icon: arrow-right\"><\/span><\/h3>\n<p><a href=\"\/us\/webinars\/#safe-formalin-handling\">Read More<\/a><\/p>\n<\/li>\n<li>\n<p>        <img decoding=\"async\" src=\"\/us\/wp-content\/uploads\/2023\/03\/icon-publication-green.png\" alt=\"Publication\"><\/p>\n<h3>Publications  <span uk-icon=\"icon: arrow-right\"><\/span><\/h3>\n<p><a href=\"\/us\/publications\/#sample-handling\">Read More<\/a><\/p>\n<\/li>\n<li>\n<p>        <img decoding=\"async\" src=\"\/us\/wp-content\/uploads\/2023\/03\/icon-casestudy-green.png\" alt=\"Case Study\"><\/p>\n<h3>Case Study <span uk-icon=\"icon: arrow-right\"><\/span><\/h3>\n<p><a href=\"\/us\/case-study\/\">Read More<\/a><\/p>\n<\/li>\n<\/ul>\n<h2>Have questions?<\/h2>\n<div>Contact us directly by completing the form below.<\/div>\n<div>\n\t\t\t\t\t\t<script>\n\t\t\t\t\t\t\twindow.hsFormsOnReady = window.hsFormsOnReady || [];\n\t\t\t\t\t\t\twindow.hsFormsOnReady.push(()=>{\n\t\t\t\t\t\t\t\thbspt.forms.create({\n\t\t\t\t\t\t\t\t\tportalId: 9033646,\n\t\t\t\t\t\t\t\t\tformId: \"d966b92c-3341-49c7-b285-c39e778f6e16\",\n\t\t\t\t\t\t\t\t\ttarget: \"#hbspt-form-1778696358000-0795148874\",\n\t\t\t\t\t\t\t\t\tregion: \"na1\",\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t})});\n\t\t\t\t\t\t<\/script>\n\t\t\t\t\t\t<div class=\"hbspt-form\" id=\"hbspt-form-1778696358000-0795148874\"><\/div><\/div>\n<p><!--more--><br \/>\n<!-- {\"type\":\"layout\",\"children\":[{\"type\":\"section\",\"props\":{\"image\":\"wp-content\\\/uploads\\\/2023\\\/06\\\/intro.jpg\",\"image_effect\":\"parallax\",\"image_parallax_bgy\":\"200\",\"image_position\":\"bottom-center\",\"image_size\":\"cover\",\"media_overlay\":\"rgba(0, 0, 0, 0.29)\",\"padding\":\"small\",\"padding_remove_bottom\":false,\"padding_remove_top\":false,\"style\":\"default\",\"title_breakpoint\":\"xl\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"vertical_align\":\"middle\",\"width\":\"\"},\"children\":[{\"type\":\"row\",\"props\":{\"column_gap\":\"collapse\",\"layout\":\"1-3,2-3\",\"margin_remove_bottom\":false,\"margin_remove_top\":false,\"width\":\"xlarge\"},\"children\":[{\"type\":\"column\",\"props\":{\"css\":\".el-column {margin: 50px 0px 50px 0px;}\",\"image_position\":\"center-center\",\"image_size\":\"cover\",\"media_overlay\":\"rgba(0, 0, 0, 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Biospecimen Collection\",\"title_decoration\":\"bullet\",\"title_element\":\"h3\",\"title_style\":\"h3\"}},{\"type\":\"text\",\"props\":{\"column_breakpoint\":\"m\",\"content\":\"TissueSAFE plus is an innovative and patented vacuum system that allows the <strong>preservation of fresh tissues<\\\/strong> in their natural state, <strong>without fixative<\\\/strong>. Right after excision, specimens are placed into dedicated bags and sealed under vacuum, thus eliminating the need for formalin in the OR. \\nTissueSAFE plus also allows <strong>traceability and documentation of the biospecimen transfer<\\\/strong> from the surgical theater to the histopathology lab.\",\"margin\":\"default\",\"margin_remove_bottom\":true}},{\"name\":\"List Image Left Style Divider\",\"type\":\"list\",\"children\":[{\"type\":\"list_item\",\"props\":{\"content\":\"Operator Safety\",\"image\":\"wp-content\\\/uploads\\\/2023\\\/11\\\/icon-user-safety-1.png\",\"image_alt\":\"Operator Safety\",\"link\":\"#safety\"}},{\"type\":\"list_item\",\"props\":{\"content\":\"Documented Formalin-Free Transfer\",\"image\":\"wp-content\\\/uploads\\\/2023\\\/06\\\/icon-formalin-transfer.png\",\"image_alt\":\"Documented Formalin-Free Transfer\",\"link\":\"#transfer-control\"}},{\"type\":\"list_item\",\"props\":{\"content\":\"Control of Tissue 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