Automatic Fixation and Decalcification System for Bone Tissues
Milestone’s DecalMATE enables histotechs to “tailor” their fixation/decalcification process to the specific characteristics of their bone tissue specimens.
For the first time, automatic protocols for fixation/decalcification of bone tissues are available for the modern laboratory. These protocols allow for improved diagnostic quality, consistency of results and faster turn-around time.
The unit consists of a resistance heated, temperature controlled process cavity, made of high chemical resistant techno polymers, with a built-in magnetic stirring device for temperature and concentration homogeneity.
DECALCIFICATION SOLUTION FOR OPTIMAL MOLECULAR STUDIES
For faster decalcification times, fixation/decalcification with EDTA is best carried out at a pH value of 7.2-7.4. Milestone has developed an innovative, pure EDTA solution, based on a stoichiometric mixture of bibasic and tribasic EDTA to reach this pH value without the addition of an acid/base buffer.
The combination of increased temperature, stirring and MoL-DECALCIFIER during the decalcification phase allows fixation, decalcification and processing of bone marrows within 48 hours.
|Formalin 10%||MoL-DECALCIFIER||°C||Fixation + Decal.|
|1h 30'||16h 30'||37||18h|
|Formalin 10%||Formic 10%||°C||Fixation + Decal.|
|1h 30'||1h 30'||37||3h|