Automatic Fixation and Decalcification System for Bone Tissues


Simple, Automatic and Safe

DecalMATE is a tool to enable histotechs to “tailor” their fixation/decalcification process to the specific characteristics of their bone tissue specimens.

For the first, time automatic protocols for fixation/decalcification of bone tissues are available to the modern laboratory for improved diagnostic quality and consistency of results plus faster turn-around time.

The unit consists of a resistance heated, temperature controlled process cavity, made of high chemical resistance techno polymers, with a built-in magnetic stirring device for temperature and concentration homogeneity.



For a faster decalcification time, the process with EDTA is best carried out at a pH value of 7.2-7.4. Milestone has developed an innovative, pure EDTA solution, based on a stoichiometric mixture of bibasic and tribasic EDTA to reach this pH value without the addition of an acid/base buffer.

The combination of an increased temperature, stirring and the MoL-DECALCIFIER, during the decalcification phase allows fixation, decalcification and processing of bone marrows within 48 hours.

Fixation Decal. Temp. Total Time
Formalin 10% MoL-DECALCIFIER °C Fixation + Decal.
1h 30' 16h 30' 37 18h
1h 4h 50 5h
Formalin 10% Formic 10% °C Fixation + Decal.
1h 30' 1h 30' 37 3h
1h 1h 50 2h

Why DecalMATE?


    Possibility to use different decalcification reagents, racks and fixation/decalcification temperatures.
  • SAFE
    Closed fixation/decalcification cavity with safety switches (shield open, cavity open).
  • FAST

    24 hours turn around time for bone marrow.
Up to 30 standard cassettes can be fixed/decalcified simultaneously.

    USB port enables both updating of software and downloading of event logs.

Have questions?