The challenge: improving the workflow of the laboratory
In today’s histology labs, the workload consists approximately of 35-50% small biopsies (below
3 mm) and 40-50% surgical specimens. Transplant, stat and urgent biopsies that require a rapid turnaround time are a minority of the total workload.
This small number of biopsies interferes with the routine workflow of the laboratory. Conventional large capacity tissue processors do not fulfill the requirements for the speed and flexibility needed to effectively improve the workflow of a laboratory or to address these specific workflow streams.
The LOGOS J sets new standards:
- Results within 50-60 minutes for stat, urgent or transplant biopsies.
- A fully automated Bone Marrow Processor for turnaround time in less than 24 hours.
- For specific specimens: prostate, skin, gastric.
- For biopsies up to 3mm to level out the workload in the lab.
- For HER-2, ER, PgR according to ASCO-CAP guidelines.
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Unmatched processing times
faster than conventional processing
|Specimen thickness||Rapid protocols. Fully automated||Improved workflow with sequential processing in continuous batch mode|
(less than 1mm)
|Full batch processed in 36 minutes
|Batch loading every 21 minutes|
(i.e. GI/Endoscopic byopsies)
|Full batch processed in 1 h 16 minutes
|Batch loading every 51 minutes|
|3 mm||Full batch processed in 3 h 28 minutes
|Batch loading every 2 hours 13 minutes|
Note: The above timing are referred to ethanol/isopropanol protocols, excluding reagent movement.
LOGOS J: THE RIGHT TOOL FOR "lean" labS
For urgent specimens: fully automated, single retort, rapid hybrid tissue processor
During the day, the histotech will start dedicated single batch runs with short cleaning cycles.
LOGOS J will run urgent biopsies with hybrid microwave technology as a fully automated unit.
Molten wax will be transferred automatically to and from the processing retort for impregnation.
LOGOS J will process bone marrow specimens through the fixation, decalcification, dehydration clearing and impregnation steps in a fully automated mode. The specimens will be ready for cutting, embedding and staining to allow rapid diagnosis in less than 24-hours.
For high throughput: a sequential, dual retort, simultaneous batch hybrid tissue processor
The first rack is processed in the fixation/dehydration/
At the end of the cycle, the rack is manually transferred to the wax retort.
A new rack is placed in the processing retort. The two racks are simultaneously processed.
LOGOS J processes biopsies with specific optimized protocols to consistently assure the highest quality standards.
Microwave processed, H&E
Alcian blue microwave staining of mucin producing cells (x 400)
Breast cells HER2 amplification
Detection by IHC, processed by microwaves. Hematoxylin counterstain (x 400)
Breast cells HER2 amplification
Detection by FISH processed by microwaves. Red-labeled HER2 probe (x 800)
Fully automated bone marrow processing for a diagnosis in less than 24 hours
For the first time fully automated fixation (formalin), decalcification (formic acid, EDTA), dehydration, clearing and impregnation of bone marrow samples can be carried out in less than 24 hours.
Total processing time (fixation to impregnation) for bone marrow specimens of 1.8 mm diameter (11 gauge).
|Formic acid 10%||37°C||4h 11’|
|Formic acid 10%||50°C||3h 16’|
|EDTA 10%||37°C||20h 41’|
|EDTA 10%||50°C||5h 46’|
Note: The above timing is referred to ethanol/isopropanol protocols, excluding reagent movement.