Rapid multifunctional microwave tissue processor
A state-of-the-art, multifunctional microwave tissue processor, the KOS is ideally suited as a complement to the existing capabilities found in histology laboratories, where the multitasking nature of the instrument can enhance and accelerate many of the typical applications encountered.
THE UNIQUE FEATURES OF KOS
- Smart. Icon driven.
- Fast. Factory prestored optimized, full documented protocols for rapid, microwave enhanced procedures. No calibrations required: just plug-in and process.
- Reliable.. Control sensors to protect your precious specimens.
- Flexible. User defined customized programs can be created and added to a most used favorites list for quick access, as required for meeting the needs of each laboratory user.
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Multifunctional: one unit, seven major applications
Rapid tissue processing
Bone marrow processing and decalcification
Same day results for all tissue types: no compromise in regard to morphology and staining expression. Staining properties of microwave processed specimens are excellent for H&E routine staining, HC, IHC, FISH, in a fraction of the time.
- From 1 to 45 cassettes
- Ideal for transplant centers (Urgent biopsies)
- Safe. Xylene-free.
- No proprietary reagents (Ethanol - isopropanol only)
Breast cells HER2
Amplification detection by FISH processed by microwaves.
Red-labeled HER2 probe (x 800)
Breast cells HER2
Amplification detection by IHC, processed by microwaves.
|For transplant biopsies.|
|For 1 mm biopsies.|
Add 15 minutes to include fixation.
|For 3 mm biopsies.|
Add 30 minutes to include fixation.
|30 minutes||53 minutes||155 minutes|
Same-day diagnosis for bone marrow trephine biopsies. Will this help your patient? Decalcification plus processing in less than 3 hours!
An ideal application of the technology and of the multifunctional processes of the KOS: optimized decalcification and processing protocols are factory stored.
|EDTA (Mol-Decalcifier)||Formic Acid (12%)|
|Decalcification: 4 hours||Decalcification: 60 minutes|
|Processing: 100 minutes||Processing: 100 minutes|
|Total time: 340 minutes||Total time: 160 minutes|
An excellent application for the KOS. The efficient stirring continuously keeps the bone surface in contact with the “fresh” decalcifier, positively influencing the equilibrium:
- Up to 45 standard cassettes
- Up to 60 Meaga cassettes
- Up to 8 Supermega cassettes
Time consuming staining procedures are enhanced by microwave irradiation. Factory stored, optimized, step by step protocols for most common stains for 1-40 slides. Preset or customized programs guarantee operator independent, consistent results.
- Up to 76% time saving for histochemical staining protocols
- No splashing, constant pH conditions
- Magnetic stirring for temperature uniformity along the entire length of the slides
Alcian Blue (x 400)
Grimelius Argyrophyl (x 400)
PAS (x 400)
- 1. Select temperature
- 2. Select histomodule
- 3. Select time
- 4. Press GO
Milestone has developed a dedicated fixation histomodule of up to 45 cassettes.
Users can select the time at temperature protocol to fulfill all requirements of standardization and documentation for CAP/ASCO for HER2/ER.
Finally, a factory stored opitimized protocol at 50°C guarantees consistent results.
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Rapid processing system for Electron Microscopy
Electron Microscopy (EM) is extensively used in clinical pathology, whenever the support of ultrastructural morphology
can offer a more precise diagnostic answer. Over the past decades, EM has not been performed as a major routine,
primary diagnostic procedure, due to the lengthy specimen preparation processes required, that take up to two or more days.
This contrasts with paraffin tissue processing that, with Milestone’s microwave histoprocessors, enables same day diagnosis. For acceptance of EM as a same-day diagnostic tool, Milestone has developed the KOS EM system, combining state-of-the-art laboratory microwave hardware, user centric software, and dedicated processing modules. The new KOS EM microwave based processor dramatically reduces EM specimen turnaround time from days to approximately four hours.
Pathologists can now complete a diagnostic report based on H&E, Histochem, I.HC, and EM for a timely, same-day definitive diagnosis.
The design of the KOS EM system allows closed vessel processing from fixation through 100% resin, limiting to a minimum the operator’s exposure to toxic reagents. To avoid handling each individual specimen, all specimens are placed in processing cassettes stacked on a stem that holds up to 16 of them. This allows a simultaneous transfer of all the specimens from vial to vial.
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