BoneSTATION
Advanced System for Fixation and Decalcification of Bone Tissues
Advanced System for Fixation and Decalcification of Bone Tissues
Milestone’s BoneSTATION consists of two work platforms complete with glass modules for fixation/decalcification. The front platform, used for the decalcification step, features a heating plate with infrared sensors for automatic temperature control up to 50°C and magnetic stirring. The rear platform, for the fixation step, has built-in magnetic stirring only. Two user-friendly work platforms, for easy handling of bone specimens, complete the unit.
BoneSTATION can be used with any type of fixative/decalcifier, even with strong mineral acids such as HCl – HNO3, as all contact surfaces are either glass or PTFE polymer.
While mineral acids offer a faster decalcification rate, their protocols are more time/temperature sensitive and processed specimens are not optimal for molecular studies. A recent report demonstrates that in this case, recovery of nucleic acids is dramatically reduced.
For this reason, Milestone favors the use of either formic acid or EDTA as “soft” decalcifiers, as they are more suitable for molecular studies. Longer decalcification times are reduced by the optimized agitation and temperature management featured in the BoneSTATION.
DNA - Yield (ng) | RNA - Yield (ng) | Decal Time | |
---|---|---|---|
14% EDTA |
67.8 |
226.2 |
2h |
Formic |
41.5 |
175.0 |
2h |
HNO3 |
11.4 |
51.7 |
2h |
HCL/EDTA |
5.3 |
30.5 |
2h |
BoneSTATION is painted with antimicrobial powder coating, to provide protection against the growth and proliferation of microbes.
Automatic Reagents Pump In and Out |
|
||
Bench Top Unit |
|
|
|
Active Charcoal Filter Box |
|
||
Active Built-In Ventilation |
|
|
|
Connection to Facilities’ Ventilation |
|
|
|
Standard Cassette Capacity |
30 |
110 |
30 |
Mega and SuperMega Cassette Compatibility |
|
|
|
MileWATCH Ready | |||
Cleaning Cycles Free |
|
|
|
EDTA and Formic Acid Compatibility |
|
|
|
Tissue Processing Protocols |
|
||
CE IVD Unit |
|
|
|